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This observation is intriguing for 2 other explanations. First, it suggests that cells normally takes up MIF by ENDOCYTOSIS. presented the considerable intracellular expression of MIF, it might be asked what benefit would the cell gain by making use of endocytosed MIF rather then intracellular MIF. Endocytosis of MIF could manifest possibly within

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Lung endothelial cells Display screen Nearly undetectable quantities of CD74 at baseline. A current analyze observed that Long-term hyperoxia triggered CD74 upregulation in endothelial cells (73). Hyperoxia is prevalent in individuals with Grownup respiratory distress syndrome (ARDS), which can be due to requirement for prime levels of supplemental

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